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doi: 10.3389/fendo.2019.00155 118 MaXLiuZIlyasILittlePJKamatoDSahebkaAet al

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GLP-1 medications work by mimicking the action of naturally occurring GLP-1, an incretin hormone released by the intestines in response to food intake

This study demonstrated that cultured hepatocytes treated either with a precursor of GSH, such as L-cysteine or N-acetylcysteine, or with its soluble ethyl ester form, boosts the levels of cellular GSH, which upregulates CYP27A1, CYP27B1, and VDR but downregulates CYP24A1

Moreover, additional longitudinal pharmacoepidemiological analyses may identify additional associations between these molecules and adverse drug events of interest

9d for an example of our method of islet segmentation and cell classification)